Love Drugs
by Otto Snow

Love Drugs is a sequel to Amphetamine Syntheses (2002) Expanded
coverage of the synthesis of MDMA and other empathogens and stimulants.

Expanding the chemistry of empathogens to new horizons. MDMA from
scratch. Small and large scale production is described in detail. Hot
new formulas abound.

MDA appeared in the 1960s and has been called the original love drug. It
was the first in a series of molecules that produce empathy in humans.
MDMA was appeared sporadically in the 1970s. MDEA followed ecstasy in
the 1980s.

These molecules were controlled as they were being abused. Substituted
phenyl amino-butanes have reduced abuse potential and greater safety
margins. Yet, in 20 years, the development of safer entactogens has not
taken place.

Love Drugs gives the reader a look at the most innovative chemistry for
entactogen production. Reviews of conventional syntheses with tips from
the original chemists. Love Drugs is an inside look into the chemistry
of the entactogens, present and future.

Reactions Included are:

Preparation and use of Raney Nickel Catalyst.
Raney Raney Catalyst in the reduction of substituted phenyl-2-propanones.
Preparation of 2,5-Dimethoxyphenylethylamine with palladium.
Preparation of 2,5-DMA by the kilo using Raney Nickel.
p-Methoxy-N-methylamphetamine preparation.
Preparation of 3,4-Dimethyl-amphetamine. Preparation of Benzedrine.
Construction of Apparatus for Catalytic Reduction. Reductions Using
Palladium. Hydrogenations Using Platinum. Reductions Using Aluminum

Electrolytic Preparation of substituted benzaldehydes from propenyl
benzenes and benzoic acid. Gallic Acid from Tea Leaves.

Preparation of Phenyl-2-Propanone from Ephedrine or pseudo-Ephedrine.
Phenyl-2-propanones from Propenylbenzenes. Preparation of Palladium
Chloride Catalyst. Phenyl-2-propanones from Allybenzenes.
3,4-Methylenedioxy-phenyl-2-propanone from
3,4-Methylenedioxy-phenylacetic Acid. 3,4-Methylenedioxyphenylacetic
Acid Preparation from Safrol.
Preparation of Phenylacetic Acid from Benzyl Cyanide.
Preparation of 4-Methoxy-phenylacetic acld; 3,4-Dimethoxy-phenylacetic and
2,3-Dimethoxyphenylacetic acid. Preparation of Acetic Anhydride
(several reactions described). Phenylacetaldehyde from Phenylglycidic
acid or ester.
Preparation of Phenyl-2-propanone from alpha-Methyl-B-(phenyl)-glycidic
3,4-Dimethoxyphenyl-2-propanone from 3,4-Dimethoxy-1,2-dihydroxypropane.

Grignard Reactions: Preparation of Benzyl Magnesium Chloride Complex,
Benzyl Methyl Ketone (P-2-P).

Preparation of 1-Phenyl-2-propanone, 2,4-Dimethoxybenzylmethyl ketone.
Preparation of Phenyl-2-propanones from Phenyl-nitropropenes.
Phenyl-butanone from 1-Phenyl-2-nitro-1-butene.

Extraction of Safrol from Botanicals; Asarum Arifolium; Asarum Blumei;
Japanese Anise; Australian Sassafras; Daphnandra Aromatica; Cinnamomum
cecicodaphne; Cinnamomum mercadoi; Cinnamomum oliveri; Cinnamomum
parthenoxylon; Cinnamomum pedunculatum; Sassafras Root Bark; Doryphora
Sassafras; Massoi Bark

Extraction of Apiol from Botanicals; Parsley; Dill; Samphire

Anethol from Pine Oil; Kobushi; Star Anise; Anise; Fennel; Sweet Cicely

Preparation of 3,4-Dimethoxy-allybenzene from Botanicals; Melaleuca
3,4-Dimethoxyphenylpropene from Eugenol.

Isomerisation of Allybenzenes; 3,4-Dimethoxypropenylbenzene from

Eugenol from Botanicals: Cinnamomum culilawan; Cinnamomum pedatinervium;
Cinnamomum tamala; Pimento; Pimento Leaf; Cloves.

Asarone from Botanicals; Asarum Europaeum; Asarum Canadense.

Oxidation of 2,4,5-Trimethoxycinnamaldehyde into

Separation of Plant Oils by Steam Distillation;
Construction of Apparatus; Operation and Purification.

Sassafras Oil; Extraction by Steam Distillation. Design and
Construction of Volatile-Oil Stills.

Preparation of Substituted Nitrostyrenes.
Preparation of 2-Nitro-1-(2,5-Dimethoxy-4-Methylphenyl)-Butene-1.

Preparation of Vanillin from Peat. Benzaldehyde from Toluene and
Sulfuric Acid. Preparation of Benzyl Chloride from Toluene.
Benzaldehyde from Benzal Chloride Using Hydrochloric Acid.
Benzaldehyde from Benzal Chloride using Zinc Chloride.
Manufacture of Benzaldehyde from Benzyl Chloride using Hexamine.
Methylation of Hydroxybenzaldehydes.

Prepartion of Piperonal. Preparation of Heliotropyl Chloride.
Preparation of Protocatechualdehyde; p-Methoxybenzaldehyde.
2,5-Dimethoxybenzaldehyde Preparation. Preparation of

Preparation of p-Methoxyphenylethylamine.
Preparation of B-3-Methoxy-4: 5-methylenedioxyphenylethylamine.
Preparation of Ally-phenylethylamines.
Preparation of Piperonylidene-methylethyl-ketone.

Methylamine Hydrochloride Preparation.
Manufacture of Methylamine; Preparation of Acetamide.
Preparation of Dimethyl Sulphate.
Preparation of Nitroethane. Preparation of Tetranitromethane.
Improved Preparation of Tetranitromethane

d-Methamphetamine Separation from d,l-Methamphetamine.
2-Phenyl-3-aminobutane Preparation

Tableting of Phenylethylamines.

Love Drugs is an assent and essential reading to anyone interested in
the synthesis of MDMA, precursors and analogs. There is an infinite
number of new entactogens on the horizon. 150+ references. Color
cover. UV Laminated. 242 Pages 6" x 9" © 2005 Thoth Press

Love Drugs
Price $199.95