THC & TROPACOCAINE

THC is a new miracle medication, used to treat sleep disorders
allergies, inflammatory diseases, auto immune disorders, migraines,
addictions, post traumatic stress disorder, anorexia, etc.

Syntheses of THC and chemical analogs are described. Human testing are
also included. The extraction of THC (eg. 40%, 70% and 92% THC Hash Oil)
from cannabis is detailed. Isomerisation: a quick route from cannabidiol.

The discovery of its endogenous ligand, anandamide (a fatty acid amide)
has revolutionized the investigation of this new neurotransmitter
system. Anandamides have been used in the treatment of insomnia,
allergies and post traumatic stress disorder yet remain undeveloped.
Anandamides will replaced THC and marijuana because of ease of
synthesis; preparation from commonly available grocery store oils (eg.
olive oil). Multiple reactions are explained.

Tropacocaine was discovered as a trace alkaloid in Coca leaves from
Java. It is longer acting and less toxic than cocaine.

Tropacocaine is prepared from atropine obtained from nightshade plants.
The synthesis of tropacocaine from Datura (eg. nightshade) is described
and referenced. Reactions have been translated into English. Millions
of Americans are addicted to cocaine and crack, yet tropacocaine has
never been studied to assess its value as a replacement medication.

Includes:

Medical Cannabis: CANNABIS. U.S. (Br.) CANNABIS Cannab; THC; Synhexyl
Stereochemical Requirements for Cannabimimetic Activity Cannabinoid
Receptors
CB2 Agonist Treament of Autoimmunine Disorders
CB-2 Receptor Agonist Compounds
Inhibition of Cell Proliforation; Cannabinoids in the Treatment of Glaucoma
Anandamide Amidase Inhibitors as Analgesic Agents
CB1 Agonists for Use in Brain Trauma
Erratic Gastrointestial Absorbtion of delta-9-Tetrahydrocannabinol
Treating Mental Diseases, Inflammation and Pain with Anandamides

Extraction of Delta-9-Tetrahydrocannabinol from Cannabis
Extraction of Cannabis Buds (41% THC Oil)
Extraction of Cannabis Buds 2 (40% THC Oil) (92% THC Oil)
Preparing Delta-9-Tetrahydrocannabinol
Reprocessing of the Residue Left After Fractional Distillation of
Cannabis Extracts
(82% THC Yellow Oil); THC Syntheses
Water Soluble Derivatives of Cannabinoids
Synthesis of Compound (4) Ketones from Nitriles
THC in the Treatment of Glaucoma in Patients who can not take Beta-blockers
Compositions useful as a cannabinoid receptor probe
Production of 6,12-Dihydro-6-hydroxy-cannabidiol
Production of trans-delta-9-Tetrahydrocannabinol
Production of 6,12-Dihydro-6-hydroxy-cannabidiol
Production of trans-delta-9-Detrahydrocannabinol
Preparation of cis-p-Menth-2-ene-1,8,-diol
Novel Tetrahydrocannabinol Type Compounds
Preparation of (-)-6a,10a-trans-6a,7,8,10a-Tetrahydrodibenzo[b,d]-pyrans
Preparation of Optically Active trans-Hexahydrodibenzopyranones
1-Hydroxy-3-(1,1-dimethylheptyl)-6,6-dimethyl-6,6aR,7,8,10,10aR-hexahydro-9-H-dibenzo[b,d]pyran-9-one
Producing 6a,10a-trans-6a,7,8,10a-Tetrahydrodibenzo (b,d)-pyrans
3-(1,2-Dimethylheptyl)-6a,7,10,10a-tetra-hydro-1-hydroxy-6,6,9-trimethyl-6H-dibenzo
[b,d]pyran

5-Alkylresorcinols:
Preparation of l-Hydroxy-2,6-dimethoxy-4-(tertiaryalkyl)benzene
1-Hydroxy-2,6-dimethoxy-4-(1,1-dimethylheptyl)benzene
Divarin Dimethyl Ether from 3,4,5-Trimethoxy-propiophenone
Reduction of Ketones to Resorcinols
Synthesis of 5-Alkylresorcinols; Synthesis of 5-Ethylresorcinol
Preparation of Hexylresorcinol by Electrolytic Reduction of
Hexanoylresorcinol
Synthesis of 5-Methylresorcinol (Orcinol)
5-Alkylresorcinol from Demethylation of 1-(Alkyl)-3,5-Dimethoxybenzene
Demethylation Using Pyridine 5-(1,1-dimethylheptyl)resorcinol
Demethylation Using 48% Hydrobromic Acid
5-(1,1-Dimethylheptyl)resorcinol ; Preparation of 5-Alkoxyresorcinols
Preparation of Phloroglucinol and its Mono-ethers
Preparation of Compounds with Marijuana Activity
Formation of Tetrahydrocannabinols by Isomerization of Cannabidiol
A. By p-toluenesulfonic acid; B. By sulfuric acid; C. By pyridine
hydrochloride;
D. By phosphoric acid; E. Sulfamic acid; zinc chloride

Converting cis-Hexahydrodibenzo[b,d]pyran-9-ones to
trans-Hexahydrodibenzo[b,d]-pyran-9-ones
dl-trans-1-Hydroxy-3-(1,1-dimethyl-heptyl)
-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H- dibenzo[b,d]pyran-9-one
dl-trans-1-Hydroxy-3-n-pentyl-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-one

dl-trans-1-Hydroxy-3-(1,1-dimethyl-heptyl)-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-one
Stereoselective Preparation of Hexahydrodibenzopyranones and intermediates
(-)-trans-1-Hydroxy-3-(1,1-dimethyl-heptyl)-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-one;
Acetylation of THC

Delta 1-THC-7-oic acid Analgesic and Anti-inflammatory Agents
Platelet Activating Factor Antagonist
Non-psychoactive Derivatives of Delta-6-THC-7-oic Acid which have
Analgesic and Anti-inflammatory Properties
Synthesis of (3R,4R)-Delta-6-THC-DMH-7-oic Acid Acetate

Andanamides: Fatty Acid Amides; Preparation of Arachidonyl Ethanolamide
Compounds Isolated from the Brain and Synthesized
Synthetic Compounds Prepared and Tested
Anandamide Amidase Inhibitors as Analgesic Agents
Treating Anxiety and Mood Disorders with Oleamide

Fatty Acid Amides Preparation from Common Household Oils
Preparation of Oleamide
The Reactions Used
N-Substituted Amides of Natural Fatty Acids
Preparation of N-Methyl Linseed Oil Fatty Acid Amide
Preparation of N-Cyclohexyl Linseed Oil Fatty Acid Amide
Preparation of Lauric Diethanolamide from Lauroyl Chloride
Preparation of Cocoa Fatty Acid Amide Using the Aminolysis Method

Industrial Manufacture of Fatty Acid Ethanolamides
reparation of Oleic Acid Monoethanolamide
Purification of Fatty Acid Amides Using Urea
Preparation of Olive Oil and Coconut Oil Ethanolamides
Preparation of Fatty Acids; Isolation of Linoleic Acid
Isolation of Oleic Acid from Olive Oil; Production of Monoalkyolamines

TROPACOCAINE

Coca, The Source of Cocaine; COCAINA. U.S., Br.;
COCAINE HYDROCHLORIDUM. U.S., Br.
Atropine and the Tropeines
Cocaine and the Local Anesthetic; Tropacocaine
Benzoyl Ester of Ecgonine Using Benzoic Anhydride
Tropacocaine from Pseudo-tropine & Benzoic Anhydride
Pseudotropine by Electrolytic Reduction of Tropine
Tropineone by Oxidation of Tropine; Extraction of Pseudotropine
Pseudotropine by the Electrolytic Reduction of Tropinone
Tropinone by the Oxydation of Tropine;
Tropinone by the Oxydation of Pseudotropine
Tropinone by the Electrolytic Reduction of Tropine or Pseudotropine
Benzoic Anhydride

Narcotic Daturas
Origin of the Name Jimson, or Jamestown Weed; The Huaca-Cachu of Peru
Datura Alkaloids ; Hyoscyamine and Atropine; Atropine Sulphate
Hyoscine or Scopolamine ; Extraction of Atropine
Growing Datura and Related Species
BELLADONNA Atropa belladonna; Atropa belladonna (Belladonna) Cultivation
Datura stramonium L. (Jimson Weed) ; Datura stramonium (Jimson weed)
Cultivation
Hyoscyamus niger (Henbane) Cultivation ; Solanum nigram L. (Black
Nightshade)

400+ refs. Color cover. Laminated. 182 pages 6" x 9" © 2004 Thoth Press

Out-of-Print edition.

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THC & Tropacocaine
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